This page lists all the changes in the "Also Starring" cast throughout the seasons of Desperate Housewives that feature such a billing group. Thus, it lists all the characters shown in the supporting characters' portal. For details on their appearances, see Regular character appearances.
- Original Cast
*Only credited through 3.16.
*Not credited in 4.01.
- - Andrew is promoted to main character.
- - Danielle, Dylan and Kayla leave the cast.
- - Penny is promoted to supporting character.
- - Julie returns as a supporting character.
- - Karen, Juanita and MJ are promoted to supporting characters.
- - Nick and Danny join the cast.
- - Preston is demoted to recurring character.
- - Ben joins the cast.
- - Juanita is promoted to main character.
- - Karen, Lee and Bob are demoted to supporting characters.